Sodium Saccharin Sodium saccharin is a non-caloric artificial sweetener derived from o-toluenesulfonamide, providing exceptional sweetness potency with good stability in heat, acids, and alkaline conditions. In the food industry, it functions as a primary sugar substitute in diet products, synergizes with other sweeteners like cyclamate to mask bitterness and enhance flavor, and remains stable through processing without breakdown or off-flavors.